With Duragesic, MSIR, Flecaïne, and Keppra, I take Celebrex at a dosage of 200 mg once daily. I find Celebrex helps me, but only if it is taken with the other medications I listed above. It is like attacking pain from different angles. Celebrex (celecoxib) is an NSAID (Non-Steroidal Anti-Inflammatory Drug). As its name indicates, it is used for inflammation type of pain.