NOt really sure, it depends on the person I think. For most people I see posting on the TY board, they can tell when it is time for their infuion, it gives them this like burst of energy and makes them feel great.

I don't get that at all. I get an inability to do anything for 2 days where I feel like someone drained the life out of me, then I feel ok, then the next week I get sick. I know a lot of people have the sick effects, which was one reason I asked about changing the schedule from every 28 days to every 6-8 weeks; which started the whole argument with the neuro in the first place.

I did get tested for the JC Virus which seems to be a determining factor in PML. No one with PML ever tested negative to the JC Virus, which would have been the end of the ty for me had mine tested positive. As it stands, I have been looking into other options because the longer I am on it the more I dislike it.