When I have a problem with an oral medication my stomach refuses to tolerate, I take this oral medication with a medication from the PPI (Proton Pump Inhibitor) family. Right now, I take Ogastro (lansoprazole) in a dosage chosen by my primary care doctor according to the effects I get and to my needs. I particularly like Ogastro because it is a very small, flat, strawberry flavored tablet, which I put under or over my tongue until it melts. Right after, I take the oral medication my stomach does not usually accept. The problem is gone! Of course, what works for one person might not work for another person. My gastro-enterologist (gastro-intestinal tract specialist) told me never to take any oral medications my stomach does not tolerate with medications in liquid form that coat the stomach walls because this will prevent the absorption of the oral medication. This is not something you want since you need your oral medication (here: Topamax) to work. Just my two cents.