Whilst researching pregnenolone, I came across a graphic that included
pantothenic acid (vitamin B-5), calling it the "
stress vitamin", and saying that it "drives the process" of converting pregnenolone into other hormones. Curious about this, I Wiki'd pantothenic acid, and found this statement:
Quote:
Diabetic peripheral polyneuropathy
Twenty-eight out of 33 patients (84.8%) previously treated with alpha-lipoic acid for peripheral polyneuropathy reported further improvement after combination with pantothenic acid. The theoretical basis for this is that both substances intervene at different sites in pyruvate metabolism and are, thus, more effective than one substance alone. Additional clinical findings indicated diabetic neuropathy may occur in association with a latent prediabetic metabolic disturbance, and that the symptoms of neuropathy can be favorably influenced by the described combination therapy, even in poorly controlled diabetes.[36]
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This was all new to me (What
isn't?

) In everything I've read here (NT) and elsewhere, I don't recall seeing this mention of B-5 in conjunction with alpha-lipoic acid with regard to PN (not that I couldn't have missed it, though I just searched and still didn't see anything).
So I checked my daily
B-100 complex (which I take mornings along with my R-Lipoic acid anyway) and find it contains 100 mg. of pantothenic acid (hope that's enough - it's 1000% of the RDA... yeah, yeah, I know

)
Anyhoo, since I
don't recall seeing it anywhere before, I thought I'd mention it for consideration/dissection/demolition.
FWIW,
Doc