I've had RSD for six long agonizing years. I am going for my 1st Calmare Treatment here in Salt Lake City, on Sept. 7th. From all the research I've done, including discussions with my Pain Management Doctors at the U of U Pain Clinic, I have NOTHING to loose and only my LIFE to gain back! I'll keep everyone posted! RSD changes the way the electrical pain signals are received in the brain. Calmare works by (temporarily or permanently) helping to change the electrical signals back to where they were before the pain existed. So glad they figured out how to do it! I know it doesn't work for all, but I know the odds are with me.