I have always had mine at the infusion center at my neuro's office. I tend to get headaches from IVIG so I premedicate with a migraine med, tylenol and benadryl. I get 47g and infuse at a slow rate, 100, so it takes about 6 hours total. I'd rather be there longer than deal with the headache so I don't mind. My insurance company offered home infusions but it would cost me my out of pocket maximum so I declined. Having it at the infusion center just costs me a co-pay just like an office visit. I take snacks too and something to read, listen to or watch.