LDN has helped with my fatigue issues. I've still had a couple of relapses since I've been on it but they generally resolve themselves within a few weeks now. I don't take steroids but usually just let them run their course.
Some Neuros are not familiar with LDN and won't take the time to research it. My Neuro would not prescribe it so I had to get my script from another doctor. I use a compounding pharmacy that mails my prescription to me. I usually get a 3-month supply with each refill.
Here's a website that can give you more information on LDN:
www.lowdosenaltrexone.org