Wow, now it's getting really interesting. The RAS has close ties to two things I have yet to see any sort of connection in. The role of Estrogen in PD and our hyperactive amygdalas.

There are a few studies that highlight estrogen's role in in inhibiting angiotensin. This could easily explain women whose PD is sensitive to estrogen levels, me included. It could also explain why pregnancy worsens the condition in some of us.

Interestingly, there is an article that suggest an ACE Inhibitor and/or Angio antagonist are the male equivalents of estrogen in PD.

I have to retrace my steps; there are two studies I wanted to read more on but too busy at moment. All I can say is that the RAS is named as a key player in how we handle stress through an overactive amygdala.

Now if we can just tidily link prions to a faulty RAS then we'll have solved the mystery of "our PD" ha ha.

Laura