this thread has really helped and i've read a lot of the recent posts. but it is a huge decision. i went on avonex almost immediately after official diagnosis but just recently learned that i have spine lesions (2, possibly 3). my neuro feels it's good to be agressive and switch up to tysabri...i can't decide, but i'm so glad you all are out there sharing your experiences/trials. in the alternative, he wants me to switch to rebif...even that sounds like not too much fun (avonex usually does make me a little sick for at least a night--would rebif be 3X as yucky?)...

after first diagnosis i have had a few new brain spots...but i went almost 3.5 years without the spine stuff. in fact, i think it may have been had spine issues before (that weird tingly feeling)

anyhow, thanks for being here and i'll keep on reading ...