Dear MrsD
From everything i have read, there are indeed many, many, skewing factors.

I was not aware of the "sugar" one - although i have my doubts (for now, in opinion only) as to it being the "main" one. My reasoning here is that the other skewing factors wil not necessarily go away if you take away the sugar. Chemically, the metabolic routes do vary based on the proportions of the individual EFA's available, i cannot be more specific than that without a reference but unfortunately i do not have them anywhere near...

i apologize for that. Also, the body simply
cannot use supplements correctly to make PGE2 if it
doesn't have ALL the building blocks!
I will however look into the sugar influence further - thank you for pointing it out as well as the observations on ADHD where i suspect there may be organic differences as well, but again, i would have to look into that.
Mostly, I wanted to describe the process of prostaglandin synthesis in order to point out that
the question is not as simple as take extra this or extra that, and to dispel generic notions regarding what a single EFA can do. Unfortunately when folks talk nutrients, a simple answer of this kind is often sought but in this case it really cannot be distilled so simply.
i want to encourage folks to consider the big picture and to realize that the big picture is different for each person.
~ waves ~