I did. It made my already bad symptoms much worse, and quickly, too. I only lasted a month on it, but it was a looooooooong month. LOL

That being said, I know of 2 people who personally had terrific results with it. The best thing about Prograf is you will know quickly, one way or another, if it will work for you.

Just remember--no using ibuprofen and stay away from grapefruit juice as well. There may be a few other precautions you need to be aware of before starting.

Good luck!