No, the Mestinon should not interfere with the bloodwork as far as I know. The bloodwork is looking for antibodies. What Mestinon does is inhibit the enzyme that breaks down acetylcholine--that's the chemical your nerves use to communicate with your muscles.

I don't quite understand what the deal is with the cold. I know that many myasthenics do better in the cold (and worse in the heat). I know that one of the diagnostic tests they use for myasthenia, for a patient with a droopy eyelid, is to put ice around the eye. A myasthenic eyelid will perk up with ice.

I don't have eye symptoms either, except for some eye strain--when I get tired, my eyes ache, and it feels like it's hard to move them. I had double vision one evening, but only one. However, my doctor can see abnormalities in the way my eyes move.

Abby