I'm on a clonidine patch right now for 4 weeks, but it's mostly to help with the withdrawal after my epidural, as that was one of the 3 meds in it. I'm back on my pain pills (nucynta) as well and I don't have any relief from either of them right now. Clonidine does lower blood pressure and I still start to black out most every time I stand up which is frustrating but I guess it's better than the alternative of worse withdrawal symptoms. And the patch is so small and only needs to be changed once a week that it's really easy.