I take it for MS. 4.5 mg. daily taken at about 3 AM. I don't take it for pain mgmt. I take it for MS symptom mgmt. It works well for me but one of the side effects are vivid dreams. I believe it has prevented me from progressing with MS. I really won't know how much it's helping me unless I stop taking it and I'm not willing to risk throwing myself into an exacerbation to find out.