As mention its good and usually the first choice med for P/N.

Disadvantages
weight gain, this is real problem for diabetics and any anyone with foot P/n since your weight is supported by a small surface area along the soles of your feet so more weight=more painful walking.

Brain fog, which is okay if your retired or have a low profile job but if your the CEO it may be difficult.

Effectiveness which varies from person to person but the drug may require increase dosage as your body builds up a tolerance.