In my case the spasms, cramping, etc., were persistent until the doctors put me on Baclofen. It took a little while to get to the correct dosage, but for three years now it has spelled big time relief.

I used to get muscle cramps and spasms that would wake me out of a sound sleep - in the middle of the night. It was an ugly sight to wake up hurting like that - squirming trying to fight off the pain. And, when the spasms would settle down my muscles would be so sore that I thought that I had just been run over by a truck!

Good luck & I hope he can find some relief.