Two glasses of red wine, every evening with the meal, everyday for 8 years; I sometimes cut out the wine for a week to see what happens. No difference to the sinemet; feel better and sleep better with the wine.
This may be partly cultural - some cultures, and so some families, have different perceptions about this legal drug. I have seen babies being given diluted wine to put them to sleep (not a great idea) and I have heard bitter elderly saying "Lips that touched wine, never touched mine." (not a great idea).
The great idea is: all things in moderation, including moderation.