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Old 10-22-2011, 03:04 PM
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mrsD mrsD is offline
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mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

There is nothing keeping anyone from using low dose DM OTC.

The quinidine is the RX part, and works by blocking the metabolism of the DM. If you wanted you could just take the DM in low dose more often. Quinidine is not an innocuous drug. And this Nuedexta is a radical new concept of including a low dose, possibly problematic drug which affects the metabolism of the second drug to keep the blood levels in a range to work.

The whole thing IMO is iffy, and potentially dangerous. This is MY opinion, but using DM alone is still an option. You just take it a bit more often is all.
http://the-scientist.com/2011/07/11/...rup-treats-ms/

This is the original paper abstract:
http://www.ncbi.nlm.nih.gov/pubmed/21704706
.1mg per kilogram in animals... a kilogram is 2.2lb. Which works out to 7mg/150lb person if this study generalizes to humans. This is really a small amount, of DM.

Nuedexta was designed for people with pseudobulbar affect...which is inappropriate emotional lability.

Some of the anti-inflammatory studies on PD and MS are not yet approved for humans using low dose DM.
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