Thanks for this Paula, I'm not clear, though, on what you mean by mixing cells...do you mean mixing cells from one person with those of another (a bad idea IMHO) or taking one's own cells and somehow mixing them? I'm all for that, actually, and if we found out in ten years that there were things with doing that that were actually not so good, well, that PWP who mixed his cells within himself would have had ten years (or more) of relief from this damn disease, hopefully, and doesn't that happen with drugs out there all the time now anyway? New drug comes out, sounds great, oops, we learn later that it gives people heart attacks...or worse.

Until something comes along, like you said, that seriously cuts into the so-lucrative-there's-no-incentive-to-develop-anything-else drugs, nothing will move forward. I'm also very much interested in Jannetta's theory of vascular compression in PD, which would have enormous impact if shown to be beneficial for even a small percentage of PWP.