I've been taking Lyrica for 1 1/2 years and take it in 3 doses of 200 mgs each, per day. Lyrica is supposed to last for 6-8 hours per dose.
I take it at 8 am, 4pm, and 11 pm (bedtime is around 12 midnite).
I also take Tramadol 100mgs,4x day the same times as Lyrica with an additional dose around noon-1pm. I try to hold off on doses if I really feel that I can on any particular day, but never skip a dose, or my feet start to
'talk to me' and complain severely.