Dx 10 years ago.
Two months ago...I maxed my sinemet cr to almost 1300mg levadopa plus contam plus 8 mg requip resulting in severe leva-dopa induced off dystonia almost another day ...in fact, no one, even my MDS, told me that the dystonia was leva-induced....until I rigorously reduced my sinemetcr to 400-500mg that all my dystonia gone! The reduction was done overnight, not progressive adaptation.