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Old 11-03-2011, 02:25 PM
boytos boytos is offline
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Join Date: Aug 2010
Posts: 493
10 yr Member
boytos boytos is offline
Member
 
Join Date: Aug 2010
Posts: 493
10 yr Member
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Candidats for anti-tgfb1, the more difficult to find.

Sumarin

In vivo, direct injection of suramin (2.5 mg) into injured murine muscle resulted in effective inhibition of muscle fibrosis and enhanced muscle regeneration, which led to efficient functional muscle recovery.

http://jap.physiology.org/content/95/2/771.short
Suramin has been found to inhibit transforming growth factor (TGF)-{beta}1 expression by competitively binding to the growth factor receptor

http://en.wikipedia.org/wiki/Suramin


Decorin

The ability of decorin to inhibit TGF-ß activity is likely the mechanism by which this molecule blocks fibrosis.Infusion of decorin into experimental rodent spinal cord injuries has been shown to suppress scar formation and promote axon growth.

http://www.ors.org/web/Transactions/50/0796.PDF

Infusion of decorin into experimental rodent spinal cord injuries has been shown to suppress scar formation and promote axon growth.

http://en.wikipedia.org/wiki/Decorin
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