When I started it I used 300mg a day for a couple of months.

Back then I had alot of burning pain. Since I found some food triggers for the burning, and as the burning diminished and wasn't all the time, I reduced to 150mg a day. Doctor's Best.

This form of Thiamine is fat soluble and hangs around in the body for a while. The regular thiamine comes out the urine very quickly, within 4 hrs for me. I can smell it.

I think that once you get enough in your system to reach a steady state, you won't need as much.

But we have had posters here taking huge amounts. 600mg or more daily. For people with a history of alcohol abuse, heavy use or intolerance, Benfotiamine is helpful. Also one cannot know who has genetic problems needing more of this than others.

So go by your symptoms, whether you have diabetic issues, alcohol issues, etc. I think this works slowly, so don't expect quick results. You should know in a month or two if it is helping.
If it helps but you think more would be worth it, you can try that then. Or the reverse. I try to stay lower with most supplements if possible.

This supplement used to be very hard to get-- came from Germany, and was very very expensive, at one time. Now it is very affordable.

You can look up beriberi on the net to see if you have any hidden symptoms of that which would point to using higher doses of benfotiamine. I think it is more common than realized and doctors don't identify it in some people.