Subject: Every 72 seconds someone in America develops Alzheimer's
Date: March 20, 2007 at 5:35 pm PST
Alzheimer's Disease Prevalence Rates Rise to More than Five Million in the United States
Someone develops Alzheimer's every 72 seconds, according to new Alzheimer's Association report
The Alzheimer's Association today reports that in 2007 there are now more than 5 million people in the United States living with Alzheimer's disease. This number includes 4.9 million people over the age of 65 and between 200,000 and 500,000 people under age 65 with early onset Alzheimer's disease and other dementias. This is a 10 percent increase from the previous prevalence nationwide estimate of 4.5 million.
The greatest risk factor for Alzheimer's is increasing age, and with 78 million baby boomers beginning to turn 60 last year, it is estimated that someone in America develops Alzheimer's every 72 seconds; by mid-century someone will develop Alzheimer's every 33 seconds.
These new estimates, as well as other data concerning the disease and its effects, are issued today as hundreds of advocates from across the country gather in the nation's capitol for the Alzheimer's Association's annual Public Policy Forum. The report titled, 2007 Alzheimer's Disease Facts and Figures, is being released at a hearing today chaired by Senator Barbara Mikulski. Senators Barbara Mikulski and Christopher Bond and Representatives Edward Markey and Christopher Smith have introduced bipartisan legislation to address problems identified in the Association's report. The Association's report details the escalation of Alzheimer's disease which now is the seventh leading cause of death in the country and the fifth leading cause of death for those over age 65. It also offers numerous statistics that convey the burden that Alzheimer's imposes on individuals, families, state and federal governments, businesses, and the nation's health care system. For example:
Without a cure or effective treatments to delay the onset or progression of the Alzheimer's, the prevalence could soar to 7.7 million people with the disease by 2030, which is more than the population of 140 of the 236 United Nations countries.
By mid-century, the number of people with Alzheimer's is expected to grow to as many as 16 million, more than the current total population of New York City, Los Angeles, Chicago and Houston combined.
As the prevalence impact of Alzheimer's grows, so does the cost to the nation. The direct and indirect costs of Alzheimer's and other dementias amount to more than $148 billion annually, which is more than the annual sales of any retailer in the world excluding Wal-Mart.
"Alzheimer's Disease Facts and Figures clearly shows the tremendous impact this disease is having on the nation; and with the projected growth of the disease, the collective impact on individuals, families, Medicare, Medicaid, and businesses will be even greater," says Harry Johns, President and CEO of the Alzheimer's Association. "However there is hope. There are currently nine drugs in Phase III clinical trials for Alzheimer's several of which show great promise to slow or stop the progression of the disease. This, combined with advancements in diagnostic tools, has the potential to change the landscape of Alzheimer's."
According to the latest statistics from the Centers for Disease Control and Prevention, from 2000-2004 death rates have declined for most major diseases -- heart disease (-8 percent), breast cancer (-2.6 percent), prostate cancer (-6.3 percent) and stroke (-10.4 percent), while Alzheimer's disease deaths continue to trend upward, increasing 33 percent during that period.
"We must make the fight against Alzheimer's a national priority before it's too late. The absence of effective disease modifying drugs, coupled with an aging population, makes Alzheimer's the health care crisis of the 21st century," Johns said.
Medicare currently spends nearly three times as much for people with Alzheimer's and other dementias than for the average Medicare beneficiary. Medicare costs are projected to double from $91 billion in 2005 to more than $189 billion by 2015, more than the current gross national product of 86 percent of the world's countries. In 2005, state and federal Medicaid spending for nursing home and home care for people with Alzheimer's and other dementias was estimated at $21 billion; that number is projected to increase to $27 billion by 2015.
The new report also highlights the impact that Alzheimer's has on states with more than 6 in 10 (62%) having double digit growth in prevalence by the end of the decade. In addition, Alaska (+47%), Colorado (+47%), Utah (+45%), Wyoming (+43%), Nevada (+38%), Idaho (+37%), Oregon (+33%), and Washington (+33%) will experience increases ranging from one-third to one-half. The states with the largest numbers of deaths due to Alzheimer's disease in 2003 were (1) California, (2) Florida, (3) Texas, (4) Pennsylvania, and (5) Ohio.
The Alzheimer's Association is the first and largest voluntary health organization dedicated to finding prevention methods, treatments and an eventual cure for Alzheimer's. For more than 25 years, the Association has provided reliable information and care consultation; created services for families; increased funding for dementia research; and influenced public policy changes.
Contact: Call our media line at 312.335.4078
Download Report: 2007 Alzheimer's Disease Facts and Figures (28 pages)
Quote Sheet (2 pages)
http://www.alz.org/national/document...quotesheet.pdf
Fact sheet (2 pages)
http://www.alz.org/national/document...Ffactsheet.pdf
http://www.alz.org/news_and_events_rates_rise.asp
Every 72 seconds
someone in America
develops Alzheimer's.
http://www.alz.org/national/document...AndFigures.pdf
More Evidence Mad Cow Same
As CJD And Alzheimer's
1-24-3
IN STRICT CONFIDENCE
TRANSMISSION OF ALZHEIMER-TYPE PLAQUES TO PRIMATES
http://www.bseinquiry.gov.uk/files/y...1/05004001.pdf
full text ;
http://www.rense.com/general34/cjmd.htm
Proof Mad Cow Is The Same
As Alzheimer's And CJD
How Many Of Them Are Really Mad Cow/vCJD/TSEs ???
How Can Government Claims Of Just 'One In A Million' Be Accurate
When CJD Is Not A Reportable Disease? And When The Elderly Do
Not Get Routinely Autopsied??
By Terry Singletary, Sr
12-27-03
Regarding Alzheimer's disease
(note the substantial increase on a yearly basis)
http://www.bseinquiry.gov.uk/files/y...7/08014001.pdf
snip...
The pathogenesis of these diseases was compared to Alzheimer's disease at a molecular level...
snip...
http://www.bseinquiry.gov.uk/files/y...3/12003001.pdf
And NONE of this is relevant to BSE?
There is also the matter whether the spectrum of ''prion disease'' is wider than that recognized at present.
http://www.bseinquiry.gov.uk/files/y...7/06005001.pdf
Human BSE
snip...
These are not relevant to any possible human hazard from BSE nor to the much more common dementia, Alzheimers.
snip...
http://www.bseinquiry.gov.uk/files/y...7/09001001.pdf
================================================== ===
From: TSS
Subject: CJD or Alzheimer's, THE PA STUDY...full text
Date: May 7, 2001 at 10:24 am PST
Diagnosis of dementia: Clinicopathologic correlations
Francois Boller, MD, PhD; Oscar L. Lopez, MD; and John Moossy, MD
Article abstract--Based on 54 demented patients consecutively autopsied at the University of Pittsburgh, we studied the accuracy of clinicians in predicting the pathologic diagnosis. Thirty-nine patients (72.2%) had Alzheimer's disease, while 15 (27.7%) had other CNS diseases (four multi-infarct dementia; three Creutzfeldt-Jakob disease; two thalamic and subcortical gliosis; three Parkinson's disease; one progressive supranuclear palsy; one Huntington's disease; and one unclassified). Two neurologists independently reviewed the clinical records of each patient without knowledge of the patient's identity or clinical or pathologic diagnoses; each clinician reached a clinical diagnosis based on criteria derived from those of the NINCDS/ADRDA. In 34 (63 %) cases both clinicians were correct, in nine (17%) one was correct, and in 11 (20%) neither was correct. These results show that in patients with a clinical diagnosis of dementia, the etiology cannot be accurately predicted during life.
NEUROLOGY 1989;39:76-79
snip...
Subject: Re: Hello Dr. Manuelidis Date: Fri, 22 Dec 2000 17:47:09 -0500 From: laura manuelidis Reply-To:
laura.manuelidis@yale.edu Organization: Yale Medical School To: "Terry S. Singeltary Sr."
References: <39B5561A.87B84A28@wt.net> <39B64574.A4835745@yale.edu>
<39B680D8.3872535B@wt.net> <39B66EF1.4CE25685@yale.edu>
<39BBB812.425109F@wt.net> <39BE84CB.D7C0C16B@yale.edu>
<3A3BA197.7F60D376@wt.net>
Dear Terry,
One of our papers (in Alzheimer's Disease Related Disord. 3:100-109, 1989) in text cites 6 of 46 (13%) of clinical AD as CJD. There may be a later paper from another lab showing the same higher than expected incidence but I can't put my hands on it right now. We also have a lot of papers from 1985 on stating that there are likely many silent (non-clinical) CJD infections, i.e. much greater than the "tip of the iceberg" of long standing end-stage cases with clinical symptoms. Hope this helps.
best wishes for the new year laura manuelidis
"Terry S. Singeltary Sr." wrote: Hello again Dr. Manuelidis, could you please help me locate the 2 studies that were done on CJD where it showed that up to 13% of the people diagnosed as having Alzheimer's actually had CJD. trying to find reference... thank you, > Terry S. Singeltary Sr.
4.5 MILLION DEMENTED ALZHEIMER'S PATIENTS, HOW MANY ARE CJD/TSEs ???
HOW CAN ONE-IN-A-MILLION BE ACCURATE WHEN CJD IS NOT REPORTABLE,
AND WHEN THE ELDERLY DO NOT GET AUTOPSIED??????
TSS
http://www.rense.com/general46/proofa.html
Alzheimer's and Transmissible Spongiform Encephalopathies
snip...
Subject: Alzheimer-type neuropathology in a 28-year old patient with iatrogenic CJD after dural grafting
Date: March 9, 2007 at 9:15 am PST
HUMAN-04
Alzheimer-type neuropathology in a 28-year old patient with iatrogenic
Creutzfeldt-Jakob disease after dural grafting
M Preusser1, T Stroebel1, E Gelpi1, 2, M Eiler3, G Broessner4, E Schmutzhard4, H Budka1, 2
1 Institute of Neurology, Medical University Vienna, Austria; 2 Austrian Reference Centre for Human Prion Diseases
(OERPE), General Hospital Vienna, Austria; 3 Department of Neurology, LKH Rankweil, Austria; 4 Department of
Neurology, Medical University Innsbruck, Austria
We report the autopsy case of a 28-year old male patient who had received a cadaverous dura
mater graft after a traumatic open skull fracture with tearing of dura at the age of 5 years. A
clinical suspicion of Creutzfeldt-Jakob disease (CJD) was confirmed by a brain biopsy 5 months
prior to death and by autopsy, thus warranting the diagnosis of iatrogenic CJD (iCJD) according
to WHO criteria. Immunohistochemistry showed widespread cortical depositions of diseaseassociated
prion protein (PrPsc) in a synaptic pattern and western blot analysis identified PrPsc of
type 2A according to Parchi et al. Surprisingly, we found Alzheimer-type senile plaques and
cerebral amyloid angiopathy in widespread areas of the brain. Plaque-type and vascular amyloid
was immunohistochemically identified as deposits of beta-A4 peptide. CERAD criteria for
diagnosis of definite Alzheimer´s disease (AD) were met in the absence of neurofibrillar tangles
or alpha-synuclein immunoreactive inclusions. There was no family history of AD, CJD, or any
other neurological disease, and genetic analysis showed no disease-specific mutations of the
prion protein, presenilin 1 and 2, or amyloid precursor protein genes. This case represents 1. the
iCJD case with the longest incubation time after dural grafting reported so far, 2. the youngest
documented patient with concomitant CJD and Alzheimer-type neuropathology to date, 3. the
first description of Alzheimer type-changes in iCJD, and 4. the second case of iCJD in Austria.
Despite the young patient age, the Alzheimer-type changes may be an incidental finding, possibly
related to the childhood trauma.
249 of 411 pages...tss
http://www.tse-forum.de/tse_forum/de...FINAL_nov2.pdf
full text ;
http://neurotalk.psychcentral.com/sh...ad.php?p=78281
FELINE ALZHEIMER'S OR MAD CAT DISEASE I.E. FSE ???
http://lists.ifas.ufl.edu/cgi-bin/wa...-mg&T=0&P=8385
From: terry <[log in to unmask]>
Subject: Re: FELINE ALZHEIMER'S OR MAD CAT DISEASE I.E. FSE ???
In-Reply-To: <[log in to unmask]>
Content-Type: text/plain; charset="Windows-1252"
I have 2 questions for you, terry singeltary. Do you agree with colm kelleher where he states there may be a relationship between vCJD and alzeheimer's in that alzheimers may be misdiagnosed. And is it true that BSE cannot be destroyed by heat or chemical so that any instrument that touches it must be thrown out.
Sent wirelessly via BlackBerry from T-Mobile.
http://lists.ifas.ufl.edu/cgi-bin/wa...-mg&T=0&P=8525
Sender: Sustainable Agriculture Network Discussion Group
<[log in to unmask]>
From: "Terry S. Singeltary Sr." <[log in to unmask]>
Subject: Re: FELINE ALZHEIMER'S OR MAD CAT DISEASE I.E. FSE ???
Comments: To: [log in to unmask]
Content-type: text/plain; charset=Windows-1252
i have written about this many times and spoke with colm on several
occasions when he was writing his book.....
> Do you agree with colm kelleher where he states there may be a
relationship
> between vCJD and alzeheimer's in that alzheimers may be misdiagnosed
NOT JUST vCJD but all human TSE, especially sporadic CJD, there are studies
showing
''CJD'' as being misdiagnosed as Alzheimer's (see below).
AND personally i think there is a potential that Alzheimers may be low
level TSE.
may be something else too, i mean, just what is Alzheimer's???
Proof Mad Cow Is The Same
As Alzheimer's And CJD ???
How Many Of Them Are Really Mad Cow/vCJD/TSEs ???
How Can Government Claims Of Just 'One In A Million' Be Accurate
When CJD Is Not A Reportable Disease? And When The Elderly Do
Not Get Routinely Autopsied??
By Terry Singletary, Sr
12-27-03
snip...end
http://lists.ifas.ufl.edu/cgi-bin/wa...-mg&T=0&P=8673
TSS