I was started on 25mg of Imuran and increased to 50 mg/day after about a week. I was never able to have my dose increased above 50mg/day because my white count dropped too low. I think the original plan was to increase my dose to 75 mg 2x/day. Make sure your bloodwork is being done at least once a month in the beginning. I hope that you're able to tolerate the Imuran and that it works for you.
Cate