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Originally Posted by Dr. Smith
Good to hear; thanks for sharing it! Were you aware of that potential when you started it?
I'd been pretty emotional for the last few years, and my doctor (and wife) kept telling me it was depression and tried to put me on anti-depressives. But I'd been on several anti-depressives before, and they all made me feel worse than before taking them. Since I've started taking pregnenolone, my tears and uncontrollable emotional swings have dried up too!  (Not to mention other benefits, like less pain.)
There's no relation between Tramadol & pregnenolone that I'm aware of; Tramadol (as you know) is an opioid analgesic, while pregnenolone is one of the most common hormones in the body (that gets turned into many others).
Doc
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Is pregnenolone safe to take longterm? The wiki says its a steroid.