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Old 11-17-2011, 07:29 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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15 yr Member
mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
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I have a comment, about this link being discussed here.
I find that a rat study, provoking interpretation of memory signalling in the brain of rats, to be very basic and therefore paraphrasing, to say cortisol is a "nerve lubricant" to be simplistic and perhaps a ploy to then entice people to buy the products that website sells.
This is the article from Nature:

http://www.nature.com/neuro/journal/...s/nn.2150.html


The following is from Science News Daily: This common science reporting site, was not credited on the Wellness site at all.
http://www.sciencedaily.com/releases...0807072125.htm

Quote:
The characterization of these newly discovered mechanisms opens up numerous possibilities for future research that could enhance both fundamental knowledge and clinical benefits. We can now imagine that in certain individuals subjected to major stress, lack of receptor mobility contributes to a lack of adaptation. Under stressful conditions, synaptic plasticity would then depend on the dynamic interactions between cortisol and the neuronal receptors that modulate brain activity. In the end, better mobility means better adaptation.
This is very very early days for this research. As of now, I don't see references to humans.

This later article, 2011, goes into more detail about memory and cortisol:

http://www.sciencedaily.com/releases...0406102137.htm
Quote:
Stress hormone receptors

The study, by the University of Edinburgh, found that one receptor was activated by low levels of cortisol, which helped memory. However, once levels of this stress hormone were too high they spilled over onto a second receptor. This activates brain processes that contribute to memory impairment.
Basically it is a very fine line with brain studies on what is useful and what is not. The brain is so very complex, it will take a long time to understand why some people do well under some circumstances, and others do not. This applies to drugs as well, since many drugs we have today that affect neurotransmitters, do not work the same in all who take them. On the Tramadol thread here, I put up a paper discussing genetic differences in serotonin transporter activity and the mu receptor (opioid receptor).

http://www.nature.com/npp/journal/v2.../1395737a.html
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