The Lyrica by itself brought on relief in the burning pain a lot. But my flare ups still got the best of me. I was already at the max at 600 mgs a day so my neurologist added Cymbalta to the mix. I'm starting at 30 mgs then after two weeks going to 60 mgs. It's been one week so far. Neither one is an opiate which is what I prefer to stay away from if possible. I still notice the presence of pain but except for flare ups it's more doable...