Christine,

I'm so sorry for what you and your little girl are suffering.

I don't have any help to offer for the big questions, but I have a small comment to keep in mind for the future. IVIG often doesn't take effect right away, and the plasmapheresis your daughter had took out all the immunoglobulins that the IVIG put in, so you won't get to see if it has any delayed effect this time around. Also, some of us have found that the first IVIG treatment, or the first few, doesn't do much, but then it starts really helping.

I mention this only to say that even though IVIG didn't help in the emergency situation, it still might be an option down the road for maintenance.

That is fascinating, about your daughter's Asperger's and the change in her after the plasmapheresis. I read this book a long time ago: http://www.amazon.com/WELCOME-SILENC...2571550&sr=8-1 It's about a woman who was cured of schizophrenia with a procedure "similar to dialysis." I wonder if it was plasmapheresis. I'm certainly not suggesting that Asperger's is related to schizophrenia, but both cases show how much we don't know yet.

Abby