I was initially told to take two 60 mg tablets of Mestinon every day, and that was way too much, I ended up with overdose symptoms. I went down to one pill a day and it was too much for the first four hours and then I crashed at the end of the day (with double vision the entire time). What made the double vision go away was splitting the pills in half and taking 1 to 1 1/2 pills a day, but only 1/2 pill at a time.

I am extremely sensitive to medication, I might be an exception in that low doses work for me. I have since then started taking 1/4 pill at a time and it works even better than the 1/2 pill.

The dosage is different for everybody. I also have taken no other medication for my MG besides the Mestinon.