I just had my last wisdom tooth pulled (better late than never, eh?), and it hurt like the dickens the first few days after the extraction. I ended up not taking my LDN for four nights in a row because I used codeine for pain relief, and LDN would render codeine’s pain-relieving properties ineffective. I couldn’t wait to get back on the LDN. It is an important part of my “Beat MS” strategy.