I thank everyone for your help, I really don't know what to do, I have tried going off prozac before, due to ms, I get suicidal so I have to be on something and this works so good for me. I will talk more to my doc about it, I have no choice to take something and the plavix, this is vert worrisom, which it shouldn't be, the doctors should be up on this, and they should communicate, and believe me, I will tell them that