Hi. I just ran a PubMed search for "pregnenolone cognitive," which produced 44 hits. The best of which was Neurosteroids: deficient cognitive performance in aged rats depends on low pregnenolone sulfate levels in the hippocampus, Vallée M, Mayo W, Darnaudéry M et al, Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14865-70 online text @ http://www.pnas.org/content/94/26/14865.full.pdf but that was a murine (rat) study and when I pulled up the 135 "related" studies or review articles, they appear to be entirely rat-based as well!

Do you know of any human studies out there?

Who supervised your testing and/or treatment? Are you currently being followed by a neuro-endocrinologist?

And when you say that "it has measurably improved my short-term memory and cognitive function . . . (Test scores before/after improved 20-25%)," what tests are you speaking of, and who performed them?

Inquiring minds want to know.

Mike