I have been on 60 of Cymbalta with 300 of Lyrica and it works very well. Much less burning. I also take meloxicam for the bone pain as well as Flexoril for the muscle spasms. The combo has worked well. I had a spinal cord stim implanted last March and that has REALLY given me hope! My hand functions (most of the time) now, before the stim I was unable to open it. Now I can type mostly with one hand but my left can hit a button every so often. Now I'm trying to piece my life back but if I can't find a job soon we are going to lose our home. I am going back to school to finish my Bachelors in Social Work. I want to help others like us.