It has been one week since I began taking my last dose of Sinamet late at night up to 2 1/2 hours or less before taking my daily dose of DM, and it seems that I feel much better the following day if my last daily dose of Sinamet is still active when I take the DM

My daily drug regimens..(I am and have been undermedicated throughout my dx with pd)

My previous med regimen:..

9:00am - 1 Sinamet 25/100...1 Mirapex .25

2:00pm.- 1 Sinamet 25/100...1 Mirapex .25

7:00pm - 1 Sinamet 25/100

1:00am - 1/2 teaspoon DM

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My new med regimen:..

9:00am - 1 Sinamet 25/100...1 Mirapex .25

2:00pm.- 1 Sinamet 25/100...1 Mirapex .25

7:00pm - 1 Mirapex .25

11:00pm..(or up to 1/2 hour prior to taking DM)..1 Sinamet 25/100

1:00am - 1/2 teaspoon DM

(I use the Mirapex .25 at 7:00pm dose as a filler dose instead of the usual Sinamet)

Ive had a few friends comment on my improved condition, and a couple have asked me if I was on a new medication..My friend Jim who I have fished with since 1978 goes to Florida every winter..He saw me before he left in December..and he just came back and stopped over this morning..He said that he noticed that I wasnt dragging my foot like I was before..that I only stuttered a little bit..that I was more alert, and looked better than I did in December when he left for Fla

It has been about 5 weeks since I began taking DM daily, and there is absolutely no doubt in my mind that it has improved my symptoms drastically..even my memory has improved