Yes, you can have both MS and Lupus. And I may or may not be an example of that.

A positive ANA does not automatically mean Lupus as well as other autoimmune disease. There is a series of tests that need to be run as well to determine what is going on and to make a dx. The results take some time. I know many people who have had a positive ANA and upon further testing, ended up not having anything. I had a negative ANA but am positive for one of the Lupus tests that I had done. Go figure. But, it is my understanding that is not uncommon with Lupus either. I have not been to the rheumy to confirm that dx - I go after the holidays for that appointment. But, I will say that the symptoms I am having that caused me to get all these blood tests done are not the same symptom I get with my MS. They are 2 separate sets of symptoms that sometimes occur at the same time. But, like MS, Lupus can be difficult to diagnose and can take quite a while to dx.

I wish your friend the best and hope she starts feeling better soon.