I didn't know any specific amount had to be reached (Thanks). Sometimes rotation is forced upon a patient with the same results. I know a patient who recently lost her insurance, and could no longer afford the oxy she had depended on for years. She switched to MSER as a less expensive alternative, and found that she needed only 2/3 of the "equivalent" dose of oxy she had been taking. Needless to say she and her doctor were pleased.

Doc