Thread: How to double your on time!!
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Old 12-21-2011, 11:11 AM
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reverett123 reverett123 is offline
In Remembrance
  
Join Date: Aug 2006
Posts: 3,772
15 yr Member
reverett123 reverett123 is offline
In Remembrance
reverett123's Avatar
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
Default Gets interesting
Just did a search for cyp3a4 plus turmeric. Turned up a lot of hits:

"It appears that Curcumin from Turmeric and Piperine from Black Pepper (commonly taken together) both inhibit a number of Cytochrome P450 enzymes. P450's such as CYP3A4 and CYP2D6 are responsible for a large amount of drug metabolism and the use of Curcumin and Piperine might explain some of the reactions people are experiencing upon co-administration with drugs such as Benzodiazepines and Amphetamine type drugs... Interesting stuff and something people, especially those using this forum, should be aware of.

http://www.bluelight.ru/vb/threads/5...yme-Inhibition
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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