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Originally Posted by fabdou
This is a very interesting topic. In addition to antibiotics, it may also explain how statins can produce PN. Is it possible/likely that mito damage from statins and other toxins could produce clinical sxs in a shorter time period than that seen with more chronic causes of PN, like CMT?
My neurologist believes I have CMT despite a negative genetic workup and negative family hx (and negative extensive workup for any other cause of PN) He says my muscle atrophy/ EMG findings are consistent with something that took years to develop. I disagree because I have lost mass and strength only since being on statins for 5 yrs. Could mito damage cause a similar clinical presentation over a shorter period of time and mimic CMT in its clinical presentation?
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Here is an interesting site. Statins are contraindicated for people who have CMT.
http://help4cmt.com/articles/?id=35&...terol-with-cmt
The general population can also have trouble with statins such as muscle pain, weakness, etc. I know people who have experienced this. This site might help and there are many sites out there.
http://www.mayoclinic.com/health/sta...ffects/MY00205
Despite the fact that you have had a negative genetic workup and a negative family history, you still could have a type of CMT. Symptoms can vary greatly even within the same family. They can be hardly having any symptoms that are noticeable at all. There could be a spontaneous mutation which is rare.