the way my doctors do it, i get two days of treatment in a row and i start pushing at 50 ml/hr in about an hour im up to my max of 400 ml/hr but the thing that is the headahce killer is the 50 mg of benedryl they give me in the iv. make sure that they give you the iv of benedryl instead of the pill, often the pill takes too long to work and im normally out of the hospital before it help and im all drowsy and cant drive. if they give it to you in the iv it almost knocks you out so i nap during my infusion