Violet, I'm sorry your daughter is having such a hard time. When an MGer gets that weak, the best place for them is in a hospital.

What Mrs. D. may not know is that your daughter was also on a sleeping pill! When you add together two sedating medicines, you are putting yourself at risk even if you don't have MG.

Aleve is not contraindicated in MG. But when you start adding meds together like she is doing, you can end up with a drug cocktail that would be hard on anyone. The liver and kidneys clear medications from the body. Has your daughter had a comprehensive chemistry done? That would include things like electrolytes, kidney/liver function, protein level, glucose, etc. You might want to get a copy of the tests they did in the hospital. That is often a standard test run on MGers and other patients in critical care.

You can't really compare one person's reaction to a drug to another person's reaction! Everyone is different. What drugs like Aleve often do is make a person retain fluids. That, in turn, can effect the electrolyte levels in the body. For example, potassium could then be too high. She should get a baseline chemistry of her electrolytes when she is doing better to see if there is yet another issue here.

What Benadryl does, besides reducing histamine, is to "shift" fluids in the body. It's complicated but that too can affect electrolytes like potassium.

Potassium, magnesium and calcium are essential to muscle function (and other functions). When those are too high or too low, they can create more muscle weakness. So while Aleve itself is not a "bad" drug, the retention of fluid which might occur can then lead to electrolytes being off balance which might result in muscle weakness!

Not every doctor knows what prescription drugs, over-the-counter drugs and even foods/drinks effect MG. We are working on a list to put here. In the meantime, if you have questions, please ask!

MG has a fairly big learning curve. It really sucks but as long as you are well-informed, you can attempt to avoid getting worse. I really hope your daughter is getting better and will continue to do so.

Annie