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Old 01-01-2012, 06:58 AM
NeuroLogic NeuroLogic is offline
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Join Date: Nov 2011
Posts: 127
10 yr Member
NeuroLogic NeuroLogic is offline
Member
 
Join Date: Nov 2011
Posts: 127
10 yr Member
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What do you think of melatonin? I'm thinking of starting it not so much for the potential sleep benefit as its antioxidant power. My cell membranes are getting trashed while I sleep, I believe, because of the unmitigated PN heat stress and resultant oxidative damage.

Antioxidant

Besides its function as synchronizer of the biological clock, melatonin also exerts a powerful antioxidant activity. . . . Melatonin is an antioxidant that can easily cross cell membranes and the blood-brain barrier. . . . Melatonin's antioxidant activity may reduce damage caused by some types of Parkinson's disease. . .

http://en.wikipedia.org/wiki/Melatonin#Antioxidant

"Patients receiving melatonin during taxane chemotherapy had a reduced incidence of neuropathy. Melatonin may be useful in the prevention or reduction of taxane-induced neuropathy and in maintaining quality of life."

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883241/

There's been some success with tests on rats:

"Results suggest that oxidative stress contributes to appearance of pain in diabetes and melatonin, as an antioxidant, is effective in reducing the acute and chronic pain in diabetic rats."

http://www.ijem.org.ir/browse.php?a_...=1&slc_lang=en
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