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Old 01-04-2012, 08:54 AM
lurkingforacure lurkingforacure is offline
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Join Date: Feb 2008
Posts: 1,485
15 yr Member
lurkingforacure lurkingforacure is offline
Senior Member
 
Join Date: Feb 2008
Posts: 1,485
15 yr Member
Default widely available OTC?

Quote:
Originally Posted by mrsD View Post
I looked around the net not long ago, and found a discussion on depression and Deplin. The posters on that blog did not find it helpful. There are studies suggesting it works for some, but the 4 or 5 people were adamant that it did not work for them.

It is pretty strong --7.5mg and in nature we don't consume that much at a time, and perhaps this is a problem?

It comes OTC by Solgar at 800mcg tablets. Less expensive.
http://www.iherb.com/Solgar-Folate-M...ets/13961?at=0

People who have that MTHFR polymorphism DNA mutation, really need this form of folate. They cannot methylate folic acid in the body properly.

Please don't take this if you are low in B12... as low B12 + folate can lead to more nerve damage. Either get tested for the B12 or take it anyway with any folate you supplement.
Methylcobalamin is best, is the active form, and only pennies a day.
The article makes it sound like you can only get the bioavailable form Rx, but I followed your link and also googled it and there are many vitamin companies offering L-methyl folate OTC. Is this the same form as the Deplin, just at a reduced dosage (800mg)?

Is Iherb the best formulation of this to go with? We also supplement with methylcobalamin and I wonder if it should be taken at the same time as the L-methyl folate? This is where a background is chemistry would come in handy, as there seem to be many variations on a vitamin theme!
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