Originally Posted by mrsD

CoQ-10 is a mitochondrial aid.

For people with neuropathy from statins (for cholesterol), this is the main line suggestion, because statins block the enzyme in our liver that makes cholesterol AND CoQ-10.

Many other drugs deplete this nutrient:
Among them:
amitriptyline and other TCAs.
beta blockers for blood pressure
clonidine
glyburide and other oral anti-diabetic agents
diuretics
some ARB's for blood pressure
some of the older antipsychotic drugs.

CoQ-10 has been used in some ataxias in high dose, and Parkinson's. But it remains costly still, because the improved absorption types are expensive.

CoQ-10 is often included in anti-aging suggestions, because it helps the heart muscle and is useful in congestive heart failure.

http://www.umm.edu/altmed/articles/c...q10-000295.htm

I think if you suspect you have a toxic cause for your PN, either drugs or toxins, then CoQ-10 may help.