I'm just passing this on in case it's helpful. I have had three courses of IVIG, a total of 13 days. I ended up with a stubborn headache for all but one of these days, in spite of taking ibuprofen beforehand, staying hydrated, and running it slowly (75 ml/hour). The last day I had a cup of coffee part-way through the infusion, and it seemed to help a lot: no headache! I know that caffeine is used to treat some kinds of headaches, but be careful because it can be tricky: it can give you a headache or make a headache you already have worse. I only recommend it for people who know how caffeine usually affects them.

Abby