Newsmom and Erin,

It works well for me, but I have Myasthenia Gravis. I do have a good friend who's doing it for MS and she is getting very good results. I can't do steroids either, and PP is really the only thing that has helped my disease much at all. Erin, you only get donor plasma if your fibrinogen, which helps your blood clot, gets low. I haven't had any donor plasma in probably 3 years. Basically what happens is that they hook you up to a machine and take blood out, then they centrifuge out the plasma and return the red cells back to you. The idea is that the antibodies are in the plasma and by removing the plasma you take out the antibodies. They usually replace the lost fluids with saline, citrate, calcium, and albumin, which is a blood product, but it's not a donor thing in the way that plasma is.

I hope that helps. As I said, my friend is getting good results, so you may want to talk further with your docs about trying it.