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Old 01-09-2012, 05:58 PM
wordsmithy wordsmithy is offline
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Join Date: Dec 2011
Location: Westchester, NY
Posts: 45
10 yr Member
wordsmithy wordsmithy is offline
Junior Member
 
Join Date: Dec 2011
Location: Westchester, NY
Posts: 45
10 yr Member
Default Celastrol or Thunder of God vine

Yes, we are talking mice, earthworms, and petri dishes. But this substance is available as a chinese herbal compound called Thunder of God vine. Seems to have anti-tumor, immuno-suppressant properties, used for cancer, rheumatoid arthritis. Under investigation for PD and Alzheimer's.

I wouldn't take it unless under the care of a TCM doctor.

Relevant articles I found:

Cell, 2008: Proteostatis Regulators and Pharmocologic Chaperones Synergize to Correct Protein Misfolding Diseases.

Journal of Neuroinflammation, 2010: Reduction of β-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease

Best,
wordsmithy
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