Some PNs are molecular so won't show up on structural tests.
If some antibodies are present attacking your nerves, they won't show up because we cannot test for all of them. Many are not identified yet.
Have you had IgG IgM etc tests? Elevated antibody titres may show up as MGUS. These thicken the blood and reduce circulation to the extremities.
Facial symptoms? Did you get Vit D tested? If low there are all sorts of paresthesias that can result from low calcium effects. Vit D is low in most Americans today. I'd also get that B12 tested, when you do the D, and if you are below 400, you should start supplements for it. US lab ranges still show very low levels as normal (doctors do not keep up with this new information)...and newer studies show higher levels are actually needed. So if you test at 250, that could definitely be contributing to your symptoms.
Have you tried going gluten free? Some people absorb the gluten peptide thru the GI tract (leaky gut) and this then causes autoimmune reactions. We've had some posters here over the years who had this...and by stopping gluten consumption their neuropathy improved.
I get burning from nightshade veggies-- potatoes, tomato sauces, peppers. MSG in foods can also be a culprit.
Also current tests for diabetes doesn't really show pre-diabetic states. Before showing up in testing, a person can already be having nerve damage if they have low sugar episodes, and high insulin levels.
Getting tested for elevated INSULIN will show this...it is called insulin resistance.
Quote:
Idiopathic neuropathy, prediabetes and the metabolic syndrome.
by: A. Gordon Smith, J. Robinson Singleton
Journal of the neurological sciences, Vol. 242, No. 1-2. (15 March 2006), pp. 9-14. doi:10.1016/j.jns.2005.11.020 Key: citeulike:6499468
View FullText article
DOI, Pubmed, Hubmed, Pubget
Abstract
Peripheral neuropathy is a common problem encountered by neurologists and primary care physicians. While there are many causes for peripheral neuropathy, none can be identified in a large percentage of patients ("idiopathic neuropathy"). Despite its high prevalence, idiopathic neuropathy is poorly studied and understood. There is evolving evidence that impaired glucose tolerance (prediabetes) is associated with idiopathic neuropathy. Preliminary data from a multicenter study of diet and exercise in prediabetes (the Impaired Glucose Tolerance Neuropathy Study) suggests a diet and exercise counseling regimen based on the Diabetes Prevention Program results in improved metabolic measures and small fiber function. Prediabetes is part of the Metabolic Syndrome, which also includes hypertension, hyperlipidemia and obesity. Individual aspects of the Metabolic Syndrome influence risk and progression of diabetic neuropathy and may play a causative role in neuropathy both for those with prediabetes, and those with otherwise idiopathic neuropathy. Thus, a multifactorial treatment approach to individual components of Metabolic Syndrome may slow prediabetic neuropathy progression or result in improvement.
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from
http://www.citeulike.org/user/wrs1/article/6499468
So simple fasting glucose or short GTT (2hr) tests do not reveal this.
A long 4-5 hr GTT will show the lows, but doctors are often not trained to identify this clue. If you are not high, they just dismiss diabetes, and you can then continue to have the PN.
There are over 100 causes of PN. Some are in the spine and cause compression of nerves, but many are molecular, inflammatory, or metabolic. Some are from the use of drugs and that list is growing every day. Some are from vaccines. Some are from heavy metals, or pesticides from the environment.
You can start doing elimination diets yourself. Start with sugar and starchy carbs. If you feel better then that points to impaired glucose tolerance. Go off nightshades, or gluten or any other food you crave (craving often indicates some intolerance) for two weeks, one category at a time. Then reintroduce it and see if symptoms increase.
One really has to be a detective to find answers to a puzzling thing like PN.
Have you stopped running? I'd stop running for a while and see if you notice any difference. When you run you inhale alot of pollution that is in the air, and it is now being investigated that nanoparticles of pollution get absorbed into the body and brain and cause all sorts of damage. Were you tested for heavy metals? They can be in the nanoparticles, or somewhere else in the environment.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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