Hi aussiemom, The reason for the plaquenil is that they believe my PN is auto immune related. I did not tell the doctor about stopping it. I am going to call today. This is more pain than I can handle and I can usually handle a lot.

En bloc now that I know Plaquenil has that long of a half life, I am thinking stopping may be the reason for the pain. However, I was not in this much pain before I started it. I don't think I've ever had this much joint and muscle pain. I don't know if this could be a flare up of AI disease. I do have cold sores on my lips also, but I don't feel sick. Just in pain. Thanks to both of you for the advice.