The Prednisone is effective in reducing the inflammation in the nerve axons as well as in other sites in the body (joints, muscles etc.) The supplements help to boost the energy levels. As we age, cellular production of ATP decreases and D-Ribose helps to replace ATP levels, promoting healthier cells. Without control of the inflammatory process, nerve cell and general cellular regeneration would be much slower. In concert, these two administrations appear to be helping.